Fighting Cancer with Fenbendazole: Big Pharma’s Worst Nightmare

This article originally appeared on makismd.substack.com and was republished with permission.

Guest Post by Dr. William Makis

NEW ARTICLE: FENBENDAZOLE and CANCER Part 2 – Treating Turbo Cancer – 10 new studies released in 2023-2024 (also Mebendazole) – suggested PROTOCOLS for COVID-19 mRNA Vaccine Induced Turbo Cancers

Last year, in October, I wrote one of the most popular articles on FENBENDAZOLE and… pic.twitter.com/tFlAQswx2T

— William Makis MD (@MakisMD) April 13, 2024

Last year I published one of the most popular articles on Fenbendazole and Cancer Treatment ever published, which went viral internationally (even Joe Rogan read my article on his show):

(Oct.3, 2023) – FENBENDAZOLE and CANCER – at least 12 Anti-Cancer mechanisms of action. Not approved by FDA. Cheap. Safe. Kills aggressive cancers. Why no Clinical Trials? Nine research papers reviewed.

10 NEW STUDIES SINCE LAST ARTICLE!

• (2024 Apr, Rodrigues et al) – Repurposing mebendazole against triple-negative breast cancer CNS metastasis
• (2024 Feb, Eid et al) – Investigating the Promising Anticancer Activity of Cetuximab and Fenbendazole Combination as Dual CBS and VEGFR-2 Inhibitors and Endowed with Apoptotic Potential
• (2024 Feb, Park et al) – The microtubule cytoskeleton: A validated target for the development of 2-Aryl-1H-benzo[d]imidazole derivatives as potential anticancer agents
• (2024 Jan, Matsuo et al) – Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes
• (2023, Dec, Iragavarapu-Charyulu et al) – A novel treatment to enhance survival for end stage triple negative breast cancer using repurposed veterinary anthelmintics combined with gut‑supporting/immune enhancing molecules
• (2023 Nov, Aliabadi et al) – In vitro and in vivo anticancer activity of mebendazole in colon cancer: a promising drug repositioning
• (2023 Nov, Jung et al) – Fenbendazole Exhibits Differential Anticancer Effects In Vitro and In Vivo in Models of Mouse Lymphoma
• (2023 Sep, Garg et al) – Network pharmacology and molecular docking study-based approach to explore mechanism of benzimidazole-based anthelmintics for the treatment of lung cancer
• (2023 Jun, Mukherjee et al) – Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical pediatric glioma
• (2023 Feb, Lee et al) – Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine

MY TAKE ON MOST RECENT RESEARCH:

Image Source: (2023 Feb, Lee et al) – Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine

There is still some research being done on Fenbendazole & Cancer, but researchers are focusing more on other related compounds in the “Benzimidazole family”, namely Mebendazole, but also Albendazole, Parbendazole. Why?

From X:

How do you use Fenbendazole for Cancer?

What is Mebendazole? (the expensive, FDA Approved version of Fenbendazole)

This article is the practical approach that addresses all of those questions.

First, I give you 10 peer reviewed studies published since my last article (2023-2024) that look at repurposing Fenbendazole, Mebendazole, Albendazole and Parbendazole for cancer.

We get it. This family of anti-parasitic drugs called “Benzimidazoles” are fantastic for cancer and big pharma is rushing to repurpose these drugs for particularly aggressive cancers like colon cancers or brain cancers.

But they’re focusing not on Fenbendazole but on the others. WHY? Follow the money.

Fenbendazole is dirt cheap.

Mebendazole (Enverm) has skyrocketed to over $400 per dose

Albendazole (Albenza) has skyrocketed to over $190 per dose

I want to highlight one of these 10 new peer reviewed studies that prove Fenbendazole (and its more expensive variants) works against cancer, because there is an additional KEY element there.

(2023 Jun, Mukherjee et al) – Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical pediatric glioma

“This study investigated the influence of nutritional ketosis on the therapeutic action of mebendazole (MBZ) and devimistat (CPI-613) against the highly invasive VM-M3 glioblastoma cells in juvenile syngeneic p20-p25 mice”

“maximum therapeutic benefit of mebendazole and CPI-613 on tumour invasion and mouse survival occurred only when the drugs were administered together with a ketogenic diet (KD)

Let me repeat that once again:

“Maximum benefit of mebendazole against cancer occurred only when it was administered with a KETOGENIC DIET”.

You must starve cancer cells of glucose.

Now let’s get to DOSING:

I propose the following FENBENDAZOLE DOSING:

LOW DOSE (222mg/day) (3 days on, 4 days off)

– Cancers in remission

– Strong family history, genetic predisposition

– prophylaxis

– Original Joe Tippens Protocol (with Curcumin 600mg/day, CBD Oil 25mg/day, Vitamin E 800 IU/day)

MEDIUM DOSE (222mg/day, 6 days a week)

– Starting dose for most non-mRNA induced tumors

– weight < 200lb

HIGH DOSE (444mg/day, 6 days a week)

– Most COVID-19 mRNA Vaccine Turbo Cancers

– Aggressive Cancers

– Stage 4

– Weight 200+ lb

VERY HIGH DOSE (888mg/day or 1000mg/day, 6 days a week)

– Extensive metastatic disease

– Extremely poor prognosis

Highest dosing I’ve seen is 30-50mg/kg/day for 5 days, based on the “Merck Manual”, however there is no evidence in the literature for this high dose. Still, a few claim to have taken this dose without side effects.

Fenbendazole can elevate liver function tests, so it would be a good idea to have a family doctor monitor those with regular blood work.

WHAT ABOUT MEBENDAZOLE?

This is the FDA Approved (for humans), more expensive version of Fenbendazole that big pharma likes better

This is going to be a significantly more expensive option and may be out of reach for some people.

No one talks about dosing of Mebendazole for Cancer, however, published literature suggests this:

LOW DOSE (100mg/day)

– Cancers in remission

– Strong family history, genetic predisposition

– prophylaxis

MEDIUM DOSE (200mg/day)

– Starting dose for non-mRNA cancers

– Several studies in humans have used this dose successfully for metastatic disease but disease eventually progresses, so it doesn’t seem to be strong enough dose

HIGH DOSE (500mg-1500mg/day)

– There is a Clinical trial for brain cancer that is using this dose regimen

– mRNA Turbo Cancer cases should probably start here

– Aggressive cancers

– Stage 4 disease

VERY HIGH DOSE (4g/day)

– safety established in 2021 study by Mansoori et al in a Phase 2 Clinical Trial for Gastrointestinal Cancer

– right now, there is no regimen in the literature with a higher dose than this

COMBINATION WITH IVERMECTIN:

If I was diagnosed with mRNA Induced Turbo Cancer, I would strongly consider a Combination Protocol with starting doses of Ivermectin (1mg/kg/day) and Fenbendazole (444mg/day)

Thought Experiment:

Imagine you are a Canadian doctor, with 8 COVID-19 mRNA Vaccines because you listened to Dr.Theresa Tam @CPHO_Canada and the Canadian Medical Association @CMA_Docs, and because of their incompetence and malice, you’ve just been diagnosed with a Stage 4 Colon Cancer with metastatic disease in the liver, lungs and bones. You probably have 2-3 months to live, or less. You are going to want to look at a COMBINATION PROTOCOL with the highest doses of Ivermectin (2mg/kg/day) and Fenbendazole (888mg/day or 1000mg/day) you can tolerate and have your doctor monitor your liver and kidney function tests.

My goal with these articles, is to provide as much clear information as possible for someone dealing with cancer or mRNA Induced Turbo Cancer.

This article deals with the practical approach to using Febendazole or Mebendazole with a reasonable dosing schedule or approach to figuring out what dose to try.

It is important to arm yourself with medical knowledge that cancer doctors (Oncologists) will simply not give you, because they either don’t know it, or they won’t risk their careers to save you.

If you care at all about cancer, you don’t want to miss this ground-breaking article! Big pharma is really going to hate this one (I expect 100s of bots to swarm my account within 24 hours)

And if anyone can get me on Joe Rogan’s Podcast, so I can help him pronounce “FENBENDAZOLE” properly, as well as other medical terms that he struggled with, I’d really appreciate it!

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Copyright 2024 Dr. William Makis